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According to Forbes, Bitcoin approached $90,000 earlier this month. Meanwhile, global debt continues to rise, and the "currency depreciation trade" surrounding the decline in purchasing power of fiat currency has become one of the factors driving up assets like Bitcoin and gold.Data from the Institute of International Finance shows that global debt increased by $10 trillion in the first half of this year, surpassing $365 trillion in total. The U.S. debt has exceeded $40 trillion, with annual interest payments rising to $1.27 trillion, surpassing defense and Medicare spending, and only lower than Social Security spending. The institute warns that as benchmark interest rates rise, interest costs will also increase.Nic Puckrin, founder of Coin Bureau and cross-asset analyst, stated that the current environment is favorable for "currency depreciation assets" like Bitcoin and gold, which is part of the reason for Bitcoin's recent rise. The larger the debt of major economies, the more likely it is to suppress real borrowing costs and allow inflation to erode the real value of debt, thereby enhancing the attractiveness of such trades.Analysts from The Kobeissi Letter pointed out that the purchasing power of the dollar has declined by 23% since 2020; if assets only increased by 30% during the same period, investors have essentially just broken even in terms of real purchasing power. The U.S. inflation rate has been above the Federal Reserve's 2% target for 60 consecutive months.

The parent company Digital Currency Group has increased Fortitude Mining's existing credit line from 26 million dollars to 50 million dollars, with an additional commitment of 24 million dollars.Fortitude Mining currently has approximately 31 million dollars available for borrowing, which is expected to be fully disbursed in the form of ZEC, for the procurement of 9,000 Zcash ASIC miners, as well as capital expenditures for building and acquiring data centers, power infrastructure, and more.

On Wednesday local time, Anthropic announced that its model Claude identified a previously undescribed enzyme system in vast DNA sequence data, with a repetitive sequence arrangement similar to CRISPR. This is the first achievement of its newly established biological laboratory, which was formed this spring and is located in the San Francisco Bay Area. Following the announcement, shares of gene editing companies fell on Wednesday, with CRISPR Therapeutics down 5.54%, Beam Therapeutics down 6.02%, and Prime Medicine down 11.58%.The related task was to search for noteworthy reverse transcriptase systems from large DNA databases. During approximately 21 hours of searching, about 950 Claude agents used around 210 million tokens, with one agent noticing a repetitive DNA sequence arranged near a certain reverse transcriptase gene. The team named this combination the array-associated reverse transcriptase system, primarily found in bacteriophages, which includes reverse transcriptase genes, adjacent accompanying genes, and a set of repetitive DNA sequences. The reverse transcriptase itself has been studied before, and the new finding is that it forms a system together with surrounding non-coding DNA sequences and functionally unknown accompanying proteins.Anthropic stated that researchers still do not know the main function of this system and have not proven that it can perform targeted modifications to DNA like mature gene editing tools. Preliminary experiments found that these repetitive sequences can produce various short RNAs, but this does not equate to having programmable gene editing capabilities. The preprint paper disclosed that to verify whether the discovery could be repeated, the team ran the same search 10 more times;

According to Gate market data, the decline in U.S. stocks has widened during the trading session, with the three major indices continuing to fall. The Nasdaq index has dropped by more than 1%, the Dow Jones index is down by more than 0.2%, and the S&P 500 index has fallen by more than 0.5%.

U.S. Treasury bonds continued to decline after the strong S&P Global U.S. PMI indicator was released.

According to Gate market data, U.S. stocks opened lower, with the Dow Jones down 0.18%, the S&P 500 index down 0.11%, and the Nasdaq down 0.13%. SK Hynix fell 1.43%, ASML fell 0.58%, Alibaba fell 3.71%, and SpaceX fell 1.3%.

Glassnode stated that over time, it seems increasingly unlikely that a decline of the same depth as in past cycles will occur again in the later stages of this market. The "four-year cycle" pattern that the market previously relied on has not been reflected in this bear market.Data shows that the drawdowns in the past three cycles exceeded twice that of this cycle, and there are still several weeks until the cycle low point; in contrast, this time BTC has only fallen about 30% from its historical high, and the price is currently rising.

Uniswap team member Niko posted that after Robinhood Chain's recent large-scale innovations drove the market up, other chains have begun to replicate its ecological projects. Some KOLs and venture capital institutions continue to claim that Robinhood Chain is in decline and are guiding users towards similar projects on other chains.Robinhood Chain's current daily trading volume still exceeds 1 billion dollars, and the trading scale of stock tokens is also growing.

Federal Reserve's Goolsbee stated that if inflation does not fall back to the 2% target level, interest rates will need to be raised.He is open to the possibility of inflation starting to decline and is willing to accept that the current inflation issue stems from supply shocks that are about to fade, but he hopes to see evidence that this shock is indeed fading.

The founder of Liebit Mining Pool, Jiang Zhuoer, stated in a post that after months of trading, profit in coin-based terms has reached 34%, while profit in U-based terms has reached 92%, nearly doubling. The key to profitability lies in position, trading, and currency. Market sentiment must be involved in trading to truly feel it. We are currently in a bull market cycle, and the personal default position is to hold a full position in ETH spot. Besides several recent short positions, more importantly, it is to hold a full position in spot for the long term; shorting is merely to protect the spot after it rises, reducing the downside pullback.

Layer1 public chain Linera team members announced on Discord that their token sale on Sonar received nearly $900,000 in token fundraising commitments, but did not reach the minimum threshold required to complete the sale, and all token sale funds have been refunded to users. The team then attempted to seek emergency financing to maintain project progress towards the mainnet launch but was unable to raise the necessary funds.Currently, the team is gradually shutting down applications and the Discord community. User point balances will be retained, but the team cannot promise any future rights for the points. The team still hopes to complete protocol development and launch applications in the future.According to the tokenized asset platform RootData, Linera has raised a total of $12 million in funding, with investors including a16z Crypto, GSR, Tribe Capital, Flow Traders, Laser Digital, and others.

According to Gate market data, the decline of major European stock indices has widened during the trading session, with the Euro Stoxx 50 index, Germany's DAX index, France's CAC 40 index, and Italy's FTSE MIB index all dropping over 1%, while the UK's FTSE 100 index fell by 0.9%.

RootData's brand new version is officially launched, and the homepage has been fully updated. Its aim is to break the data barriers between TradFi and Crypto, helping users achieve efficient investment research under the trend of integration between traditional finance and cryptocurrency finance.After this upgrade, users can view the core indicators of TradFi and Crypto assets on the RootData homepage. The homepage integrates nine major sections: market overview, capital flow, stablecoin liquidity, platform market share, popular asset discovery, public chain market overview, protocol revenue, TradFi trading dynamics, and RootData Research reports, covering capital trends, asset discovery, trading platforms, public chain ecology, and research interpretation, helping users complete cross-market investment research from macro capital trends to micro asset fundamentals.It is reported that previously, RootData had launched the "Tokenized Assets" and "Exchange Stock Business Rankings" sections, accumulating data on tokenized asset tracking and trading performance, continuously helping users seize investment research opportunities in the new cycle of TradFi and Crypto integration.

According to the official announcement, the Gate contract Meme section has launched real-time trading of the GSTOCKBSC perpetual contract (settled in USDT), supporting 1-10 times leverage. Gate has also added the GSTOCKBSC trading bot and copy trading.GSTOCKBSC is a community token on the BSC Stock-Meme launch platform Genius.Fun, newly launched by Genius Foundation.

Commissioner Hester M. Peirce of the U.S. Securities and Exchange Commission (SEC) made a statement regarding the committee's approval of the "innovation exemption."This exemption is a temporary, conditional arrangement that allows "tokenized securities venues" (TSV) to trade NMS "National Market System" stocks on-chain: TSV provides automated market maker liquidity pools and sets participant admission standards, and is exempt from the definition of "exchange" under the Securities Exchange Act; specific suppliers providing liquidity to TSV are exempt from the definition of "dealer." If issuers do not wish for their stocks to trade on TSV, they can choose to opt-out. The exemption is aimed at U.S. entities, and both existing institutions and new entrants can participate.Peirce emphasized that the committee does not presuppose that parties relying on this exemption necessarily fall under the definitions of "exchange" or "dealer," but rather hopes to first observe who is using it and how it is being used before making regulatory judgments.Peirce clearly delineated the boundaries of this order: it is not about decentralized finance. Systems that are driven by automated software and are truly decentralized do not raise fundamental concerns of securities regulation, namely that intermediaries trusted by investors may be foolish, careless, or compromised; investors using permissionless smart contracts for peer-to-peer transactions do not fundamentally require an exemption. TSV is merely one model of on-chain securities trading, and the committee is open to other models, as on-chain trading models that can comply with existing Securities Exchange Act requirements may not require an exemption at all.